Encapsulation of Gold Nanoparticles in a DNA Origami Cage

Authors: Zhao, Z., Jacovetty, E. L., Liu, Y., and Yan, H.
Title: Encapsulation of Gold Nanoparticles in a DNA Origami Cage
Source: Angewandte Chemie International Edition
Year: 2011
Volume: 50
Pages: 2041-2044

ABSTRACT:

A critical challenge in nanoparticle (NP) surface functionalization is to label the NP surface with a single copy of a functional group or to display multiple, unique molecules on the NP surface with control of the orientation and intermolecular distance. This challenge was addressed with the construction of a spatially addressable, self-assembling DNA origami nanocage that encapsulates gold nanoparticles and interrupts its surface symmetry (see scheme).

DOI: 10.1002/anie.201006818. January 2011


Date of online publication: Fri, 2011-01-21
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