Site-Specific Synthesis and In Situ Immobilization of Fluorescent Silver Nanoclusters on DNA Nanoscaffolds by Use of the Tollens Reaction

Authors: Pal, S., Varghese, R., Deng, Z., Zhao, Z., Kumar, A., Yan, H., and Liu, Y.
Title: Site-Specific Synthesis and In Situ Immobilization of Fluorescent Silver Nanoclusters on DNA Nanoscaffolds by Use of the Tollens Reaction
Source: Angewandte Chemie International Edition
Year: 2011
Volume: 50
Pages: 4176–4179

ABSTRACT:

Origami embellished with silver: DNA strands with specific sequences and covalently attached sugar moieties were used for the site-specific incorporation of the sugar units on a DNA origami scaffold. This approach enabled the subsequent site-specific synthesis and in situ immobilization of fluorescent Ag clusters at predefined positions on the DNA nanoscaffold by treatment with the Tollens reagent (see picture).

DOI: 10.1002/anie.201007529


Date of online publication: Wed, 2011-04-06
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