De novo design of functional proteins: Toward artificial hydrogenases

Authors: Faiella, M., Roy, A., Sommer, D., Ghirlanda, G.
Title: De novo design of functional proteins: Toward artificial hydrogenases
Source: Biopolymers
Year: 2013
Volume: 100
Pages: 558 - 571

ABSTRACT:

Over the last 25 years, de novo design has proven to be a valid approach to generate novel, well-folded proteins, and most recently, functional proteins. In response to societal needs, this approach is been used increasingly to design functional proteins developed with an eye toward sustainable fuel production. This review surveys recent examples of bioinspired de novo designed peptide based catalysts, focusing in particular on artificial hydrogenases.


Date of online publication: Tue, 2013-11-26
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